CDE-1 suppresses the production of risiRNA by coupling polyuridylation and degradation of rRNA

Abstract Background Modification of RNAs, particularly at the terminals, is critical for various essential cell processes; for example, uridylation is implicated in tumorigenesis, proliferation, stem cell maintenance, and immune defense against viruses and retrotransposons. Ribosomal RNAs can be reg...

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Bibliographic Details
Main Authors: Yun Wang, Chenchun Weng, Xiangyang Chen, Xufei Zhou, Xinya Huang, Yonghong Yan, Chengming Zhu
Format: Article
Language:English
Published: BMC 2020-09-01
Series:BMC Biology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12915-020-00850-z