Combinatorial biosynthesis yields novel hybrid argimycin P alkaloids with diverse scaffolds in Streptomyces argillaceus

Abstract Coelimycin P1 and argimycins P are two types of polyketide alkaloids produced by Streptomyces coelicolor and Streptomyces argillaceus, respectively. Their biosynthesis pathways share some early steps that render very similar aminated polyketide chains, diverging the pathways afterwards. By...

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Bibliographic Details
Main Authors: Suhui Ye, Giovanni Ballin, Ignacio Pérez‐Victoria, Alfredo F. Braña, Jesús Martín, Fernando Reyes, José A. Salas, Carmen Méndez
Format: Article
Language:English
Published: Wiley 2022-12-01
Series:Microbial Biotechnology
Online Access:https://doi.org/10.1111/1751-7915.14167