Identifying Bacterial Airways Infection in Stable Severe Asthma Using Oxford Nanopore Sequencing Technologies

Identifying Bacterial Airways Infection in Stable Severe Asthma Using Oxford Nanopore Sequencing Technologies

ABSTRACT Previous metagenomic studies in asthma have been limited by inadequate sequencing depth for species-level bacterial identification and by heterogeneity in clinical phenotyping. We hypothesize that chronic bacterial airways infection is a key “treatable trait” whose prevalence, clinical phen...

Full description

Bibliographic Details
Main Authors: Maisha F. Jabeen, Nicholas D. Sanderson, Dona Foster, Derrick W. Crook, Jennifer L. Cane, Catherine Borg, Clare Connolly, Samantha Thulborn, Ian D. Pavord, Paul Klenerman, Teresa L. Street, Timothy S. C. Hinks
Format: Article
Language:English
Published: American Society for Microbiology 2022-04-01
Series:Microbiology Spectrum
Subjects:
asthma
bacteria
Haemophilus influenzae
Illumina
microbiome
Oxford Nanopore
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02279-21

Internet

https://journals.asm.org/doi/10.1128/spectrum.02279-21

Similar Items