Efficacy and safety of sarilumab in combination with methotrexate in patients with active rheumatoid arthritis and inadequate effect of methotrexate monotherapy (results of phase III MOBILITY study)

Objective: to study the efficacy and safety of rheumatoid arthritis (RA) treatment with monoclonal antibodies to interleukin 6 receptors (IL6R) – sarilumab (SAR) in combination with methotrexate (MT).Subjects and methods. The study included adult patients with moderate or severe RA and inadequate ef...

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Bibliographic Details
Main Authors: E. L. Nasonov, M. L. Stanislav, T. A. Raskina, G. V. Kuropatkin, I. V. Shirinsky, A. P. Rebrov, N. A. Shostak, B. A. Alikhanov, E. N. Ushakov, R. G. Kamalova, S. A. Smakotina, V. I. Simanenkov, A. S. Pavsun, I. I. Zaharjan, S. S. Yakushin, M. Yu. Sandin
Format: Article
Language:Russian
Published: IMA PRESS LLC 2019-05-01
Series:Научно-практическая ревматология
Subjects:
Online Access:https://rsp.mediar-press.net/rsp/article/view/2696