Pmp22 mutant allele-specific siRNA alleviates demyelinating neuropathic phenotype in vivo

Charcot-Marie-Tooth disease (CMT) is a genetic disorder that can be caused by aberrations in >80 genes. CMT has heterogeneous modes of inheritance, including autosomal dominant, autosomal recessive, X-linked dominant, and X-linked recessive. Over 95% of cases are dominantly inherited. In this stu...

Täydet tiedot

Bibliografiset tiedot
Päätekijät:	Ji-Su Lee, Eun Hyuk Chang, Ok Jae Koo, Dong Hwan Jwa, Won Min Mo, Geon Kwak, Hyo Won Moon, Hwan Tae Park, Young Bin Hong, Byung-Ok Choi
Aineistotyyppi:	Artikkeli
Kieli:	English
Julkaistu:	Elsevier 2017-04-01
Sarja:	Neurobiology of Disease
Aiheet:	Charcot-Marie-Tooth disease Gene therapy PMP22 Demyelination Non-viral delivery
Linkit:	http://www.sciencedirect.com/science/article/pii/S0969996117300153

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http://www.sciencedirect.com/science/article/pii/S0969996117300153

Pmp22 mutant allele-specific siRNA alleviates demyelinating neuropathic phenotype in vivo

Internet

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