Co-localization of clusters of TCR-regulated genes with TAD rearrangements
Abstract Background Gene expression has long been known to be influenced by the relative proximity of DNA regulatory elements. Topologically associating domains (TADs) are self-interacting genomic regions involved in regulating gene expression by controlling the proximity of these elements. Prior st...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-10-01
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Series: | BMC Genomics |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12864-023-09693-8 |