Dynamic correlation between intrahost HIV-1 quasispecies evolution and disease progression.

Quantifying the dynamics of intrahost HIV-1 sequence evolution is one means of uncovering information about the interaction between HIV-1 and the host immune system. In the chronic phase of infection, common dynamics of sequence divergence and diversity have been reported. We developed an HIV-1 sequ...

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Bibliographic Details
Main Authors: Ha Youn Lee, Alan S Perelson, Su-Chan Park, Thomas Leitner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-12-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2602878?pdf=render