Cryptococcus neoformans-derived microvesicles enhance the pathogenesis of fungal brain infection.

Cryptococcal meningoencephalitis is the most common fungal disease in the central nervous system. The mechanisms by which Cryptococcus neoformans invades the brain are largely unknown. In this study, we found that C. neoformans-derived microvesicles (CnMVs) can enhance the traversal of the blood-bra...

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Bibliographic Details
Main Authors: Sheng-He Huang, Chun-Hua Wu, Yun C Chang, Kyung J Kwon-Chung, Robert J Brown, Ambrose Jong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3492498?pdf=render