Sparse genetically defined neurons refine the canonical role of periaqueductal gray columnar organization

Sparse genetically defined neurons refine the canonical role of periaqueductal gray columnar organization

During threat exposure, survival depends on defensive reactions. Prior works linked large glutamatergic populations in the midbrain periaqueductal gray (PAG) to defensive freezing and flight, and established that the overarching functional organization axis of the PAG is along anatomically-defined c...

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Bibliographic Details
Main Authors: Mimi Q La-Vu, Ekayana Sethi, Sandra Maesta-Pereira, Peter J Schuette, Brooke C Tobias, Fernando MCV Reis, Weisheng Wang, Anita Torossian, Amy Bishop, Saskia J Leonard, Lilly Lin, Catherine M Cahill, Avishek Adhikari
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-06-01
Series:eLife
Subjects:
periaqueductal gray
predator
escape
fear
optogenetics
cholecystokinin
Online Access:https://elifesciences.org/articles/77115

Internet

https://elifesciences.org/articles/77115

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