Curcumin inhibits high glucose oxidative stress and apoptosis in pancreatic beta cells via CHOP/PCG-1α and pERK1/2
Loss of pancreatic beta-cells by apoptosis appears to play an important role in the development of insulin deficiency and the onset and/or progression of the diabetes mellitus. To this end, we report that curcumin prevents high glucose (HG) induced oxidative stress and apoptosis in mouse pancreatic...
Main Authors: | Kaijian Hou, Yongru Chen, Dan Zhu, Genben Chen, Fengwu Chen, Ningning Xu, Khan Barkat, Jiehong Zheng, Xi Xie, Rongping Chen |
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Format: | Article |
Language: | English |
Published: |
IMR Press
2020-06-01
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Series: | Frontiers in Bioscience-Landmark |
Subjects: | |
Online Access: | https://www.imrpress.com/journal/FBL/25/11/10.2741/4887 |
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