Formation and Dynamics of Waves in a Cortical Model of Cholinergic Modulation.
Acetylcholine (ACh) is a regulator of neural excitability and one of the neurochemical substrates of sleep. Amongst the cellular effects induced by cholinergic modulation are a reduction in spike-frequency adaptation (SFA) and a shift in the phase response curve (PRC). We demonstrate in a biophysica...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-08-01
|
Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC4546669?pdf=render |