Formation and Dynamics of Waves in a Cortical Model of Cholinergic Modulation.

Formation and Dynamics of Waves in a Cortical Model of Cholinergic Modulation.

Acetylcholine (ACh) is a regulator of neural excitability and one of the neurochemical substrates of sleep. Amongst the cellular effects induced by cholinergic modulation are a reduction in spike-frequency adaptation (SFA) and a shift in the phase response curve (PRC). We demonstrate in a biophysica...

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Bibliographic Details
Main Authors: James P Roach, Eshel Ben-Jacob, Leonard M Sander, Michal R Zochowski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-08-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4546669?pdf=render

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