A Plausible Mechanism for the Iridium-Catalyzed Hydrogenation of a Bulky <i>N</i>-Aryl Imine in the (<i>S</i>)-Metolachlor Process

A Plausible Mechanism for the Iridium-Catalyzed Hydrogenation of a Bulky <i>N</i>-Aryl Imine in the (<i>S</i>)-Metolachlor Process

The hydrogenation of <i>N</i>-(2-ethyl-6-methylphenyl)-1-methoxypropan-2-imine is the largest-scale asymmetric catalytic process for the industrial production of agrochemical (<i>S</i>)-metolachlor. The challenging hydrogenation across the sterically crowded carbon–nitrogen d...

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Bibliographic Details
Main Authors: Amanda L. Kwan, Robert H. Morris
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Molecules
Subjects:
asymmetric catalysis
density functional calculations
hydrogenation
iridium
reaction mechanisms
Online Access:https://www.mdpi.com/1420-3049/27/16/5106

Internet

https://www.mdpi.com/1420-3049/27/16/5106

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