Genetic Modifiers of Oral Nicotine Consumption in Chrna5 Null Mutant Mice

The gene CHRNA5 is strongly associated with the level of nicotine consumption in humans and manipulation of the expression or function of Chrna5 similarly alters nicotine consumption in rodents. In both humans and rodents, reduced or complete loss of function of Chrna5 leads to increased nicotine co...

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Bibliographic Details
Main Authors: Erin Meyers, Zachary Werner, David Wichman, Hunter L. Mathews, Richard A. Radcliffe, Joseph H. Nadeau, Jerry A. Stitzel
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Psychiatry
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2021.773400/full