Effect of Antibiotic Susceptibility and <i>CYP3A4/5</i> and <i>CYP2C19</i> Genotype on the Outcome of Vonoprazan-Containing <i>Helicobacter pylori</i> Eradication Therapy

Effect of Antibiotic Susceptibility and <i>CYP3A4/5</i> and <i>CYP2C19</i> Genotype on the Outcome of Vonoprazan-Containing <i>Helicobacter pylori</i> Eradication Therapy

Background: <i>Helicobacter pylori</i> eradication containing the potassium-competitive acid blocker, vonoprazan, achieves a higher eradication rate than therapy with proton pump inhibitors (PPIs). Because vonoprazan is mainly metabolized by CYP3A4/5, CYP genotype may affect the eradicat...

Full description

Bibliographic Details
Main Authors: Mitsushige Sugimoto, Daiki Hira, Masaki Murata, Takashi Kawai, Tomohiro Terada
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Antibiotics
Subjects:
Vonoprazan
<i>CYP3A5</i>
<i>CYP2C19</i>
<i>Helicobacter pylori</i>
drug resistance
Online Access:https://www.mdpi.com/2079-6382/9/10/645

Internet

https://www.mdpi.com/2079-6382/9/10/645

Similar Items