Activation of Adenosine Monophosphate-Activated Protein Kinase Drives the Aerobic Glycolysis in Hippocampus for Delaying Cognitive Decline Following Electroacupuncture Treatment in APP/PS1 Mice

Activation of Adenosine Monophosphate-Activated Protein Kinase Drives the Aerobic Glycolysis in Hippocampus for Delaying Cognitive Decline Following Electroacupuncture Treatment in APP/PS1 Mice

Aerobic glycolysis (AG), an important pathway of glucose metabolism, is dramatically declined in Alzheimer’s disease (AD). AMP-activated protein kinase (AMPK) is a key regulator to maintain the stability of energy metabolism by promoting the process of AG and regulating glucose metabolism. Interesti...

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Bibliographic Details
Main Authors: Jianhong Li, Bingxue Zhang, Weiwei Jia, Minguang Yang, Yuhao Zhang, Jiayong Zhang, Le Li, Tingting Jin, Zhifu Wang, Jing Tao, Lidian Chen, Shengxiang Liang, Weilin Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Cellular Neuroscience
Subjects:
electroacupuncture
Alzheimer’s disease
aerobic glycolysis
learning and memory
adenosine monophosphate-activated protein kinase (AMPK)
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2021.774569/full

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https://www.frontiersin.org/articles/10.3389/fncel.2021.774569/full

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