Deletion of exons 45 to 55 in the DMD gene: from the therapeutic perspective to the in vitro model
Abstract Background Gene editing therapies in development for correcting out-of-frame DMD mutations in Duchenne muscular dystrophy aim to replicate benign spontaneous deletions. Deletion of 45–55 DMD exons (del45–55) was described in asymptomatic subjects, but recently serious skeletal and cardiac c...
Main Authors: | , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2024-10-01
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Series: | Skeletal Muscle |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13395-024-00353-3 |