Cross-talk between autophagy and ferroptosis contributes to the liver injury induced by fluoride via the mtROS-dependent pathway

Fluoride can induce hepatotoxicity, but the mechanisms responsible are yet to be investigated. This study sought to investigate the role and mechanism of mitochondrial reactive oxygen species (mtROS), autophagy, and ferroptosis in fluoride-induced hepatic injury with a focus on the role of mtROS-med...

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Bibliographic Details
Main Authors: Wanjing Xu, Zeyu Hu, Jingjing Zhang, Yanling Tang, Hengrui Xing, Panpan Xu, Yue Ma, Qiang Niu
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651322013306