Synthesis and biological evaluation of oxazinonaphthalene-3-one derivatives as potential anticancer agents and tubulin inhibitors
Objective(s): In the present study, a new series of oxazinonaphthalene-3-one analogs was designed and synthesized as novel tubulin inhibitors.Materials and Methods: The cytotoxic activity of the synthesized compounds was evaluated against four human cancer cell lines including A2780 (human ovarian c...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Mashhad University of Medical Sciences
2020-11-01
|
Series: | Iranian Journal of Basic Medical Sciences |
Subjects: | |
Online Access: | https://ijbms.mums.ac.ir/article_16623_b36d3247ce30ba1a81e66b754a831a1d.pdf |