Synthesis and biological evaluation of oxazinonaphthalene-3-one derivatives as potential anticancer agents and tubulin inhibitors

Objective(s): In the present study, a new series of oxazinonaphthalene-3-one analogs was designed and synthesized as novel tubulin inhibitors.Materials and Methods: The cytotoxic activity of the synthesized compounds was evaluated against four human cancer cell lines including A2780 (human ovarian c...

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Bibliographic Details
Main Authors: Salimeh Mirzaei, Maqsudjon Qayumov, Fahimeh Ganji, Javad Behravan, Razieh Ghodsi
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2020-11-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Online Access:https://ijbms.mums.ac.ir/article_16623_b36d3247ce30ba1a81e66b754a831a1d.pdf