Evolutionary Trajectories of Primary and Metastatic Pancreatic Neuroendocrine Tumors Based on Genomic Variations

Evolutionary Trajectories of Primary and Metastatic Pancreatic Neuroendocrine Tumors Based on Genomic Variations

Liver metastases are common in pancreatic neuroendocrine tumors (PanNETs) patients and they are considered a poor prognostic marker. This study aims to analyze the spatiotemporal patterns of genomic variations between primary and metastatic tumors, and to identify the key related biomolecular pathwa...

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Bibliographic Details
Main Authors: Midie Xu, Jiuliang Yan, Beiyuan Hu, Chuntao Wu, Haitao Gu, Zihao Qi, Tao Chen, Wenting Yang, Yan Zheng, Hanguang Dong, Weiqi Sheng, Jiang Long
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Genes
Subjects:
pancreatic neuroendocrine tumors
liver metastasis
genomic heterogeneity
tyrosine kinase
DNA repair
Online Access:https://www.mdpi.com/2073-4425/13/9/1588

Internet

https://www.mdpi.com/2073-4425/13/9/1588

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