Induction of Functional Specific Antibodies, IgG-Secreting Plasmablasts and Memory B Cells Following BCG Vaccination

Induction of Functional Specific Antibodies, IgG-Secreting Plasmablasts and Memory B Cells Following BCG Vaccination

Tuberculosis (TB) is a major global health problem and the only currently-licensed vaccine, BCG, is inadequate. Many TB vaccine candidates are designed to be given as a boost to BCG; an understanding of the BCG-induced immune response is therefore critical, and the opportunity to relate this to circ...

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Bibliographic Details
Main Authors: Julia Bitencourt, Marco Polo Peralta-Álvarez, Morven Wilkie, Ashley Jacobs, Daniel Wright, Salem Salman Almujri, Shuailin Li, Stephanie A. Harris, Steven G. Smith, Sean C. Elias, Andrew D. White, Iman Satti, Sally S. Sharpe, Matthew K. O’Shea, Helen McShane, Rachel Tanner
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Immunology
Subjects:
antibodies
B cells
humoral immunity
tuberculosis
TB
BCG
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.798207/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.798207/full

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