Cardiac functional and structural impairments, endothelial apoptosis and blood-brain barrier dysfunction in models of cerebrovascular amyloidosis in the presence or absence of hyperhomocysteinemia
Cerebrovascular dysfunction has been implicated as a major early contributor to Alzheimer's Disease (AD) pathology, with endothelial cell (EC) stress resulting in focal ischemia, cerebral blood flow impairments, and blood brain barrier (BBB) permeability. Recent evidence suggests that cardiovas...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2024-01-01
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Series: | Cerebral Circulation - Cognition and Behavior |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2666245024000400 |