Comparison of different sample preparation methods for platinum determination in cultured cells by graphite furnace atomic absorption spectrometry
Background Platinum-based agents are widely used in chemotherapy against solid tumors and insufficient intracellular drug accumulation is one of the leading causes of platinum resistance which is associated with poor survival of tumor patients. Thus, the detection of intracellular platinum is pivota...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
PeerJ Inc.
2017-01-01
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Series: | PeerJ |
Subjects: | |
Online Access: | https://peerj.com/articles/2873.pdf |