Comparison of different sample preparation methods for platinum determination in cultured cells by graphite furnace atomic absorption spectrometry

Background Platinum-based agents are widely used in chemotherapy against solid tumors and insufficient intracellular drug accumulation is one of the leading causes of platinum resistance which is associated with poor survival of tumor patients. Thus, the detection of intracellular platinum is pivota...

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Bibliographic Details
Main Authors: Man Xiao, Zaiju Huang, Jing Cai, Jinghui Jia, Yuzeng Zhang, Weihong Dong, Zehua Wang
Format: Article
Language:English
Published: PeerJ Inc. 2017-01-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/2873.pdf