Frequency of Atypical Mutations in the Spike Glycoprotein in SARS-CoV-2 Circulating from July 2020 to July 2022 in Central Italy: A Refined Analysis by Next Generation Sequencing

Frequency of Atypical Mutations in the Spike Glycoprotein in SARS-CoV-2 Circulating from July 2020 to July 2022 in Central Italy: A Refined Analysis by Next Generation Sequencing

In this study, we provided a retrospective overview in order to better define SARS-CoV-2 variants circulating in Italy during the first two years of the pandemic, by characterizing the spike mutational profiles and their association with viral load (expressed as ct values), N-glycosylation pattern,...

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Bibliographic Details
Main Authors: Maria Concetta Bellocchi, Rossana Scutari, Luca Carioti, Marco Iannetta, Greta Marchegiani, Lorenzo Piermatteo, Luigi Coppola, Simona Tedde, Leonardo Duca, Vincenzo Malagnino, Lorenzo Ansaldo, Neva Braccialarghe, Stefano D′Anna, Maria Mercedes Santoro, Andrea Di Lorenzo, Romina Salpini, Elisabetta Teti, Valentina Svicher, Massimo Andreoni, Loredana Sarmati, Francesca Ceccherini-Silberstein, on behalf of the PTV-UTV-ID-COVID Group
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Viruses
Subjects:
COVID-19
variants of concern
SARS-CoV-2
spike
epidemiology
N-glycosylation
Online Access:https://www.mdpi.com/1999-4915/15/8/1711

Internet

https://www.mdpi.com/1999-4915/15/8/1711

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