Identification of a Novel Non-desmoglein Autoantigen in Pemphigus Vulgaris

Identification of a Novel Non-desmoglein Autoantigen in Pemphigus Vulgaris

Pemphigus vulgaris (PV) is an autoimmune bullous disease of the skin and mucous membranes characterized by the presence of circulating and tissue-bound autoantibodies against keratinocyte cell surface antigens, specifically desmoglein (Dsg) 1 and 3. The pathogenic role of anti-Dsg antibodies is well...

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Bibliographic Details
Main Authors: Giulia Di Lullo, Valentina Calabresi, Feliciana Mariotti, Giovanna Zambruno, Antonio Lanzavecchia, Giovanni Di Zenzo
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Immunology
Subjects:
pemphigus vulgaris
non-desmoglein autoantigens
autoantibodies
memory B cells
α-catenin
skin
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01391/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.01391/full

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