The lactate receptor HCAR1: A key modulator of epileptic seizure activity

The lactate receptor HCAR1: A key modulator of epileptic seizure activity

Summary: Epilepsy affects millions globally with a significant portion exhibiting pharmacoresistance. Abnormal neuronal activity elevates brain lactate levels, which prompted the exploration of its receptor, the hydroxycarboxylic acid receptor 1 (HCAR1) known to downmodulate neuronal activity in phy...

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Bibliographic Details
Main Authors:	Maxime Alessandri, Alejandro Osorio-Forero, Anita Lüthi, Jean-Yves Chatton
Format:	Article
Language:	English
Published:	Elsevier 2024-05-01
Series:	iScience
Subjects:	Molecular biology Neuroscience
Online Access:	http://www.sciencedirect.com/science/article/pii/S2589004224009015

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