Anti-SARS-CoV-2 antibodies elicited by COVID-19 mRNA vaccine exhibit a unique glycosylation pattern

Anti-SARS-CoV-2 antibodies elicited by COVID-19 mRNA vaccine exhibit a unique glycosylation pattern

Summary: Messenger RNA-based vaccines against COVID-19 induce a robust anti-SARS-CoV-2 antibody response with potent viral neutralization activity. Antibody effector functions are determined by their constant region subclasses and by their glycosylation patterns, but their role in vaccine efficacy i...

Full description

Bibliographic Details
Main Authors: Inbal Farkash, Tali Feferman, Noy Cohen-Saban, Yahel Avraham, David Morgenstern, Grace Mayuni, Natasha Barth, Yaniv Lustig, Liron Miller, Dror S. Shouval, Asaf Biber, Ilya Kirgner, Yishai Levin, Rony Dahan
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:Cell Reports
Subjects:
SARS-CoV-2
BNT162b2 mRNA vaccine
antibodies
IgG-Fc
Fcγ receptors
Fc-Glycosylation
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721016089

Internet

http://www.sciencedirect.com/science/article/pii/S2211124721016089

Similar Items