Bacterial fitness in chronic wounds appears to be mediated by the capacity for high-density growth, not virulence or biofilm functions.

Bacterial fitness in chronic wounds appears to be mediated by the capacity for high-density growth, not virulence or biofilm functions.

While much is known about acute infection pathogenesis, the understanding of chronic infections has lagged. Here we sought to identify the genes and functions that mediate fitness of the pathogen Pseudomonas aeruginosa in chronic wound infections, and to better understand the selective environment i...

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Bibliographic Details
Main Authors: Sarah J Morgan, Soyeon I Lippman, Gilbert E Bautista, Joe J Harrison, Christopher L Harding, Larry A Gallagher, Ann-Chee Cheng, Richard Siehnel, Sumedha Ravishankar, Marcia L Usui, John E Olerud, Philip Fleckman, Randall D Wolcott, Colin Manoil, Pradeep K Singh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-03-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC6448920?pdf=render

Internet

http://europepmc.org/articles/PMC6448920?pdf=render

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