The Gut Microbiome and Metabolites Are Altered and Interrelated in Patients With Rheumatoid Arthritis

The Gut Microbiome and Metabolites Are Altered and Interrelated in Patients With Rheumatoid Arthritis

The relationship among the gut microbiome, global fecal metabolites and rheumatoid arthritis (RA) has not been systematically evaluated. In this study, we performed 16S rDNA sequencing and liquid chromatography-tandem mass spectrometry (LC-MS/MS)-based nontargeted metabolomic profiling on feces of 2...

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Bibliographic Details
Main Authors: Die Yu, Juping Du, Xia Pu, Liyuan Zheng, Shuaishuai Chen, Na Wang, Jun Li, Shiyong Chen, Shaobiao Pan, Bo Shen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
rheumatoid arthritis
autoimmune disease
gut microbiome
metabolome
biomarker
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2021.763507/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2021.763507/full

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