Effects of genetic variants in ADCY5, GIPR, GCKR and VPS13C on early impairment of glucose and insulin metabolism in children.

OBJECTIVE:Recent genome-wide association studies identified novel candidate genes for fasting and 2 h blood glucose and insulin levels in adults. We investigated the role of four of these loci (ADCY5, GIPR, GCKR and VPS13C) in early impairment of glucose and insulin metabolism in children. RESEARCH...

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Bibliographic Details
Main Authors: Jan Windholz, Peter Kovacs, Anke Tönjes, Kathrin Dittrich, Susann Blüher, Wieland Kiess, Michael Stumvoll, Antje Körner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3137620?pdf=render