DNA Methyltransferase HsdM Induce Drug Resistance on <i>Mycobacterium tuberculosis</i> via Multiple Effects

Besides the genomic variants, epigenetic mechanisms such as DNA methylation also have an effect on drug resistance. This study aimed to investigate the methylomes of totally/extensively drug-resistant <i>M. tuberculosis</i> clinical isolates using the PacBio single-molecule real-time tec...

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Bibliographic Details
Main Authors: Hongqian Chu, Yongfei Hu, Bing Zhang, Zhaogang Sun, Baoli Zhu
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Antibiotics
Subjects:
Online Access:https://www.mdpi.com/2079-6382/10/12/1544