Lyophilized Human Bone Allograft as an Antibiotic Carrier: An In Vitro and In Vivo Study

Lyophilized Human Bone Allograft as an Antibiotic Carrier: An In Vitro and In Vivo Study

<b>Background</b>: Antibiotics delivered from implanted bone substitute materials (BSM) can potentially be used to prevent acute infections and biofilm formation, providing high concentrations of antibiotics at the surgical site without systemic toxicity. In addition, BSM should allow os...

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Bibliographic Details
Main Authors: Débora C. Coraça-Huber, Stephan J. M. Steixner, Stevo Najman, Sanja Stojanovic, Ronja Finze, Denis Rimashevskiy, Dina Saginova, Mike Barbeck, Reinhard Schnettler
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Antibiotics
Subjects:
allograft
drug delivery
local antibiotic delivery
rabbit tibia
MIC90
bone graft infection
Online Access:https://www.mdpi.com/2079-6382/11/7/969

Internet

https://www.mdpi.com/2079-6382/11/7/969

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