Integrative analysis of transcriptomic and metabolomic profiles reveals enhanced arginine metabolism in androgen-independent prostate cancer cells

Abstract Background Prostate cancer is a common solid tumor that affects a significant number of men worldwide. Conventional androgen deprivation therapy (ADT) increases the risk of developing castration-resistant prostate cancer (CRPC). Effective clinical management of patients with CRPC is challen...

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Bibliographic Details
Main Authors: Xingchen Dai, Xinyi Shi, Mingxiu Luo, Pu Li, Yujing Gao
Format: Article
Language:English
Published: BMC 2023-12-01
Series:BMC Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12885-023-11707-3