Controlled Growth Factor Delivery and Cyclic Stretch Induces a Smooth Muscle Cell-like Phenotype in Adipose-Derived Stem Cells

Controlled Growth Factor Delivery and Cyclic Stretch Induces a Smooth Muscle Cell-like Phenotype in Adipose-Derived Stem Cells

Adipose-derived stem cells (ASCs) are an abundant and easily accessible multipotent stem cell source with potential application in smooth muscle regeneration strategies. In 3D collagen hydrogels, we investigated whether sustained release of growth factors (GF) PDGF-AB and TGF-β1 from GF-loaded micro...

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Bibliographic Details
Main Authors: Brandan Walters, Paul A. Turner, Bernd Rolauffs, Melanie L. Hart, Jan P. Stegemann
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Cells
Subjects:
adipose-derived stem cells
smooth muscle tissue engineering
microspheres
growth factors
cyclic stretch
cell morphology
Online Access:https://www.mdpi.com/2073-4409/10/11/3123

Internet

https://www.mdpi.com/2073-4409/10/11/3123

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