Inward and outward currents of native and cloned K(ATP) channels (Kir6.2/SUR1) share single-channel kinetic properties

Inward and outward currents of native and cloned K(ATP) channels (Kir6.2/SUR1) share single-channel kinetic properties

Background: The ATP-sensitive K+ (K(ATP)) channel is found in a variety of tissues extending from the heart and vascular smooth muscles to the endocrine pancreas and brain. Common to all K(ATP) channels is the pore-forming subunit Kir6.x, a member of the family of small inwardly rectifying K+ channe...

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Bibliographic Details
Main Authors: Robert Bränström, Erik Berglund, Robin Fröbom, Ingo B. Leibiger, Barbara Leibiger, Craig A. Aspinwall, Olof Larsson, Per-Olof Berggren
Format: Article
Language:English
Published: Elsevier 2022-07-01
Series:Biochemistry and Biophysics Reports
Subjects:
ATP-sensitive K+ (K(ATP)) channel
β-cells
Single channel kinetics
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580822000607

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http://www.sciencedirect.com/science/article/pii/S2405580822000607

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