Opioids and opioid receptors; understanding pharmacological mechanisms as a key to therapeutic advances and mitigation of the misuse crisis

Opioids are a mainstay in acute pain management and produce their effects and side effects (e.g., tolerance, opioid-use disorder and immune suppression) by interaction with opioid receptors. I will discuss opioid pharmacology in some controversial areas of enquiry of anaesthetic relevance. The main...

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Bibliographic Details
Main Author: David G. Lambert
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:BJA Open
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2772609623000205