Circulating Tumour Cells Indicate the Presence of Residual Disease Post-Castration in Prostate Cancer Patient-Derived Xenograft Models

Circulating Tumour Cells Indicate the Presence of Residual Disease Post-Castration in Prostate Cancer Patient-Derived Xenograft Models

Castrate-resistant prostate cancer (CRPC) is the lethal form of prostate cancer. Epithelial mesenchymal plasticity (EMP) has been associated with disease progression to CRPC, and prostate cancer therapies targeting the androgen signalling axis, including androgen deprivation therapy (ADT), promote E...

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Bibliographic Details
Main Authors: Sara Hassan, Tony Blick, Jack Wood, Erik W. Thompson, Elizabeth D. Williams
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
kallikrein related peptidase 3
metastasis
circulating tumour cell
castrate-resistant prostate cancer
epithelial mesenchymal plasticity
prostate specific antigen
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.858013/full

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https://www.frontiersin.org/articles/10.3389/fcell.2022.858013/full

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