The scaffold protein AXIN1: gene ontology, signal network, and physiological function

Abstract AXIN1, has been initially identified as a prominent antagonist within the WNT/β-catenin signaling pathway, and subsequently unveiled its integral involvement across a diverse spectrum of signaling cascades. These encompass the WNT/β-catenin, Hippo, TGFβ, AMPK, mTOR, MAPK, and antioxidant si...

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Bibliographic Details
Main Authors: Lu Qiu, Yixuan Sun, Haoming Ning, Guanyu Chen, Wenshan Zhao, Yanfeng Gao
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Cell Communication and Signaling
Subjects:
Online Access:https://doi.org/10.1186/s12964-024-01482-4