Comparison of DNA methylation based classification models for precision diagnostics of central nervous system tumors

Comparison of DNA methylation based classification models for precision diagnostics of central nervous system tumors

Abstract As part of the advancement in therapeutic decision-making for brain tumor patients at St. Jude Children’s Research Hospital (SJCRH), we developed three robust classifiers, a deep learning neural network (NN), k-nearest neighbor (kNN), and random forest (RF), trained on a reference series DN...

Full description

Bibliographic Details
Main Authors: Quynh T. Tran, Alex Breuer, Tong Lin, Ruth Tatevossian, Sariah J. Allen, Michael Clay, Larissa V. Furtado, Mark Chen, Dale Hedges, Tylman Michael, Giles Robinson, Paul Northcott, Amar Gajjar, Elizabeth Azzato, Sheila Shurtleff, David W. Ellison, Stanley Pounds, Brent A. Orr
Format: Article
Language:English
Published: Nature Portfolio 2024-10-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-024-00718-3

Internet

https://doi.org/10.1038/s41698-024-00718-3

Similar Items