Hyperinflammatory environment drives dysfunctional myeloid cell effector response to bacterial challenge in COVID-19.

Hyperinflammatory environment drives dysfunctional myeloid cell effector response to bacterial challenge in COVID-19.

COVID-19 displays diverse disease severities and symptoms including acute systemic inflammation and hypercytokinemia, with subsequent dysregulation of immune cells. Bacterial superinfections in COVID-19 can further complicate the disease course and are associated with increased mortality. However, t...

Full description

Bibliographic Details
Main Authors: Srikanth Mairpady Shambat, Alejandro Gómez-Mejia, Tiziano A Schweizer, Markus Huemer, Chun-Chi Chang, Claudio Acevedo, Judith Bergada-Pijuan, Clément Vulin, Daniel A Hofmaenner, Thomas C Scheier, Sanne Hertegonne, Elena Parietti, Nataliya Miroshnikova, Pedro D Wendel Garcia, Matthias P Hilty, Philipp Karl Buehler, Reto A Schuepbach, Silvio D Brugger, Annelies S Zinkernagel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1010176

Internet

https://doi.org/10.1371/journal.ppat.1010176

Similar Items