A trio of tumor suppressor miRNA downregulates CREB5 dependent transcription to modulate neoadjuvant hormonal therapy sensitivity

A trio of tumor suppressor miRNA downregulates CREB5 dependent transcription to modulate neoadjuvant hormonal therapy sensitivity

Neoadjuvant hormonal therapy (NHT) prior to radical prostatectomy (RP) is an approach that can potentially maximize survival outcomes in prostate cancer (PCa) patients with high-risk disease. Unfortunately, subsets of patients do not respond well to such hormonal therapy. We previously identified se...

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Bibliographic Details
Main Authors: Xueli Wang, Bo Han, Baokai Dou, Lin Gao, Feifei Sun, Mei Qi, Jing Zhang, Jing Hu
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
miRNA
CREB5
Prostate cancer
Neoadjuvant hormonal therapy
Bicalutamide
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558622001002

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http://www.sciencedirect.com/science/article/pii/S1476558622001002

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