Mifepristone Increases Life Span in Female Drosophila Without Detectable Antibacterial Activity

Mifepristone dramatically increases the life span of mated female Drosophila while reducing the expression of innate immune response genes. Previous results indicated that mifepristone also reduced the load of aero-tolerant bacteria in mated females. Experiments were conducted to further investigate...

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Bibliographic Details
Main Authors: Gary N. Landis, Luke Riggan, Hans S. Bell, William Vu, Tianyi Wang, Ina Wang, Felicia I. Tejawinata, Sebastian Ko, John Tower
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Aging
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fragi.2022.924957/full