Regenerating islet-derived 1α (REG-1α) protein increases tau phosphorylation in cell and animal models of tauopathies

Regenerating islet-derived 1α (REG-1α) protein increases tau phosphorylation in cell and animal models of tauopathies

REG-1α, a secreted protein containing a C-type lectin domain, is expressed in various organs and plays different roles in digestive system cells in physiological and pathological conditions. Like other members of the Reg family, REG-1α is expressed also in the brain where it has different functions....

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Bibliographic Details
Main Authors: Mireille Moussaed, Sylvaine Huc-Brandt, Nicolas Cubedo, Michele Silhol, Samy Murat, Marie-Christine Lebart, Gabor Kovacs, Jean-Michel Verdier, Francoise Trousse, Mireille Rossel, Anne Marcilhac
Format: Article
Language:English
Published: Elsevier 2018-11-01
Series:Neurobiology of Disease
Subjects:
REG-1α
Tau
Phosphorylation
Human brain
Cortical neurons
Zebrafish
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996118303516

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http://www.sciencedirect.com/science/article/pii/S0969996118303516

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