Wnt/β-catenin Signaling in Normal and Cancer Stem Cells
The ability of Wnt ligands to initiate a signaling cascade that results in cytoplasmic stabilization of, and nuclear localization of, β-catenin underlies their ability to regulate progenitor cell differentiation. In this review, we will summarize the current knowledge of the mechanisms underlying Wn...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2011-04-01
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Series: | Cancers |
Subjects: | |
Online Access: | http://www.mdpi.com/2072-6694/3/2/2050/ |