Brain atrophy trajectories predict differential functional performance in Alzheimer's disease: Moderations with apolipoprotein E and sex

Brain atrophy trajectories predict differential functional performance in Alzheimer's disease: Moderations with apolipoprotein E and sex

Abstract Introduction We examine whether distinct brain atrophy patterns (using brain parenchymal fraction [BPF]) differentially predict functional performance and decline in Alzheimer's disease (AD), and are independently moderated by (1) a key AD genetic risk marker (apolipoprotein E [APOE]),...

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Bibliographic Details
Main Authors: Shraddha Sapkota, Joel Ramirez, Vanessa Yhap, Mario Masellis, Sandra E. Black, for the Alzheimer's Disease Neuroimaging Initiative
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
Subjects:
Alzheimer's disease
Alzheimer's Disease Neuroimaging Initiative
apolipoprotein E
brain parenchymal fraction
functional decline
sex
Online Access:https://doi.org/10.1002/dad2.12244

Internet

https://doi.org/10.1002/dad2.12244

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