Update on the pathogenesis and genetics of Paget’s disease of bone

Update on the pathogenesis and genetics of Paget’s disease of bone

Studies over the past two decades have led to major advances in the pathogenesis of Paget’s disease of bone (PDB) and particularly on the role of genetic factors. Germline mutations of different genes have been identified, as a possible cause of this disorder, and most of the underlying pathways are...

Full description

Bibliographic Details
Main Authors: Luigi Gennari, Domenico Rendina, Daniela Merlotti, Guido Cavati, Christian Mingiano, Roberta Cosso, Maria Materozzi, Filippo Pirrotta, Veronica Abate, Marco Calabrese, Alberto Falchetti
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Paget’s disease of bone
osteoclast (OCs)
genetics
viral inclusion
environmental factors
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.932065/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2022.932065/full

Similar Items