CNAplot — Software for visual inspection of chromosomal copy number alteration in cancer using juxtaposed sequencing read depth ratios and variant allele frequencies

CNAplot — Software for visual inspection of chromosomal copy number alteration in cancer using juxtaposed sequencing read depth ratios and variant allele frequencies

Cancer genomes are frequently struck by chromosomal lesions. Next generation sequencing provides potentially high-resolution assays in a single analysis to detect copy number alterations (CNA). The implementation and usage of sequencing may partly be hampered by the lack of transparency in copy numb...

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Bibliographic Details
Main Authors: Marcus H. Hansen, Peter Hokland, Charlotte G. Nyvold
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:SoftwareX
Subjects:
Copy number alteration
Copy number variation
Whole exome sequencing
Next generation sequencing
Copy neutral loss of heterozygosity
Online Access:http://www.sciencedirect.com/science/article/pii/S2352711020300522

Internet

http://www.sciencedirect.com/science/article/pii/S2352711020300522

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