Evaluation of tumor mutational burden in small early hepatocellular carcinoma and progressed hepatocellular carcinoma

While researchers know that tumor mutational burden (TMB) is low in hepatocellular carcinoma (HCC), prior studies have not investigated TMB in cirrhosis, small early HCC and progressed HCC. HCC (n = 18) and cirrhosis (n = 6) cases were identified. TMB was determined by a 1.7 megabase, 409-gene next-...

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Bibliographic Details
Main Authors: Mary Wong, Jong T Kim, Brian Cox, Brent K Larson, Stacey Kim, Kevin M Waters, Eric Vail, Maha Guindi
Format: Article
Language:English
Published: Taylor & Francis 2021-12-01
Series:Hepatic Oncology
Subjects:
Online Access:https://www.futuremedicine.com/doi/10.2217/hep-2020-0034