Batch correction and harmonization of –Omics datasets with a tunable median polish of ratio

Large scale −omics datasets can provide new insights into normal and disease-related biology when analyzed through a systems biology framework. However, technical artefacts present in most −omics datasets due to variations in sample preparation, batching, platform settings, personnel, and other expe...

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Bibliographic Details
Main Authors: Eric B. Dammer, Nicholas T. Seyfried, Erik C. B. Johnson
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Systems Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fsysb.2023.1092341/full