Detection of neutralizing antibodies against multiple SARS-CoV-2 strains in dried blood spots using cell-free PCR

Detection of neutralizing antibodies against multiple SARS-CoV-2 strains in dried blood spots using cell-free PCR

Neutralizing antibodies are critical for conferring immunity against SARS-CoV-2. Here, Dahn et al. report a PCR assay termed SONIA (Split-Oligonucleotide Neighboring Inhibition Assay) for measuring neutralizing antibodies against multiple SARS-CoV-2 strains in fingerprick dried blood spot samples.

Bibliographic Details
Main Authors: Kenneth Danh, Donna Grace Karp, Malvika Singhal, Akshaya Tankasala, David Gebhart, Felipe de Jesus Cortez, Devangkumar Tandel, Peter V. Robinson, David Seftel, Mars Stone, Graham Simmons, Anil Bagri, Martin A. Schreiber, Andreas Buser, Andreas Holbro, Manuel Battegay, Mary Kate Morris, Carl Hanson, John R. Mills, Dane Granger, Elitza S. Theel, James R. Stubbs, Laurence M. Corash, Cheng-ting Tsai
Format: Article
Language:English
Published: Nature Portfolio 2022-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-31796-1

Internet

https://doi.org/10.1038/s41467-022-31796-1

Similar Items